Dec 9, 2025 5 min read Daily Rundown

🛎️ New Shopping Era

Plus: Law-Abiding Citizen, Sora’s Fantasy Crashes

Good Morning, AI Enthusiasts!

We are stepping into a New Shopping Era, where AI doesn’t just recommend — it transacts.

RETAIL

OpenAI and Instacart Put Shopping on Autopilot

👀 What’s happening: Instacart’s new integration with ChatGPT is now live, letting users plan meals, build grocery lists, and check out without ever leaving the chat. It’s the first large-scale rollout of OpenAI’s “agentic commerce” vision, AI tools that not only recommend but also execute purchases. The launch builds on their earlier collaboration from 2023, now elevated as Instacart’s former CEO, Fidji Simo, heads OpenAI’s Applications division.

🔥 How this hits reality: This marks the beginning of a retail rewrite. Shopping is shifting from browsing to briefing, consumers will soon describe needs, not click menus. AI agents will manage replenishment, compare prices across stores, and even adjust choices based on diet or weather. For traditional e-commerce, this breaks the funnel entirely: discovery, decision, and delivery all happen in one conversation. Brick-and-mortar stores now face a new competitor — the chat window.

🛎️ Key takeaway: Retail’s new checkout counter isn’t a cashier or an app; it’s a prompt.

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DRUG

FDA Endorses AI as Drug Development Infrastructure

👀 What’s happening: The FDA has officially qualified AIM-NASH, the first artificial intelligence system cleared to assess drug efficacy in clinical trials. The cloud-based model analyzes liver biopsy images to score fat buildup, inflammation, and scarring in patients with MASH — a disease long plagued by slow, subjective pathology reviews. Unlike the many startups using AI to design drugs, AIM-NASH is the first to be written into the FDA’s own rulebook as an MASH-validated evaluation tool.

🔥 How this hits reality: This marks a structural shift in pharma. AI is no longer just an internal discovery engine; it’s now part of the regulatory framework itself. Drug developers can plug AIM-NASH into MASH trials to generate standardized, FDA-accepted evidence — cutting months of review and millions in cost. For the first time, code isn’t just inventing new molecules, it’s deciding if they work.

🛎️ Key takeaway: AI has moved from lab assistant to law-abiding citizen, officially embedded in how the next generation of drugs gets approved.

SORA

Sora’s TikTok Fantasy Crashes to Earth

👀 What’s happening: Just months after its hyped debut, OpenAI’s Sora app is already losing users faster than it can render frames. Leaked data shows Sora’s first-day retention at only 10 percent and its 30-day retention collapsing to 1 percent, while TikTok stands strong at 50 and 32 percent. What was once hailed as “the AI era’s TikTok” now looks more like a costly sandbox that most users abandon after the first try.

🔥 How this hits reality: Sora’s problem is simple, too many bugs and too high a bill. Videos often break the laws of physics: basketballs float midair, bodies twist unnaturally, and timelines glitch out of sync. Each attempt costs users real credits, yet the output feels random. TikTok delivers infinite free entertainment, but Sora asks users to pay for frustration. When creativity becomes a gamble, retention dies fast.

🛎️ Key takeaway: Sora didn’t lose to TikTok’s algorithm; it lost to its own price tag and physics errors.

QUICK HITS

Google outlined multi-layer safeguards for Chrome’s agentic features to keep automated actions safe and controlled.
Anthropic is bringing Claude Code to Slack, enabling full coding workflows directly from chat.
Google added a shoppable AI video discovery feed to Doppl, letting users browse and virtually try on directly purchasable outfit recommendations.
Unconventional AI raised $475M to build neuromorphic AI chips targeting thousand-fold efficiency gains.
Trump will issue an executive order this week to unify U.S. AI rules, backed by Big Tech but opposed by bipartisan state leaders.

TRENDING

Daily AI Launches

SciSpace has launched BioMed Agent, an AI research assistant with access to 150+ tools for analyzing biomedical data and designing wet-lab workflows.
ACE Studio has released v2.0, an AI music workstation that combines vocal, instrument, and full-song generation models into a unified workflow.
MultiDrive has launched a free Windows tool to clone, backup, and securely wipe drives via a GUI or CLI.
RightNow has launched the first GPU-native code editor featuring hardware-aware AI, accurate emulation, and profiling for CUDA development.

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